The objectives of GnosisGIS are to:

• Facilitate collaboration of health scientists dedicated to development of GIS-based infectious disease forecast systems
• Publish the official journal Geospatial Health for peer-reviewed articles on health applications in the geospatial sciences for disease risk mapping and ecological niche modeling
• Offer training courses on health applications of geospatial tools through an 'International School of Geospatial Health'
• Sponsor an 'International Symposia on Geospatial Health' series at annual meetings
• Publish maps, data and metadata on the web on GIS health applications
  

The formation of GnosisGIS took place during a Team Residency at the Bellagio Study and Conference Center sponsored by the Rockefeller Foundation. The aim of the Team Residency was to develop a network of collaborating health workers and earth scientists dedicated to development of global computer-based models that can be used for improved control programs for schistosomiasis and other snail-borne diseases of medical and veterinary importance. The scope of the organization has since been expanded to include other infectious diseases of medical and veterinary importance.